really depends how you use Itachi
well its written there Life and Defense

Life is more on filling the low hp pool of Itachi
Ninjutsu is more on buffing up his Amaterasu damage
Defense no idea why its recommended in game with low hp pool of Itachi

in my opinion
my team has Iruka so I put Life mood and put him as a Tank because his Tsukuyomi isnt prompt activation and put him in 1st slot because it increase his clone crow activation and let enemy annoyed because of his evasions